期刊
EUROPEAN RADIOLOGY
卷 23, 期 10, 页码 2666-2675出版社
SPRINGER
DOI: 10.1007/s00330-013-2907-x
关键词
Dual energy; Tomography; X-ray computed; Lung ventilation; Lung perfusion; Pulmonary embolism
资金
- Bayer
- Bracco
- GE Healthcare
- Medrad
- Siemens
- Peak of Six Major Talents program of Jiangsu Province of China [WSW-122]
- Medical Major Talents program of Jiangsu Province of China [RC2011129]
- Program for New Century Excellent Talents in University [NCET-12-0260]
To evaluate the feasibility and findings of combined dual-energy computed tomography (DECT) lung ventilation/perfusion imaging in patients with suspected pulmonary embolism (PE). This study was institutional review board-approved and written informed consent was obtained from each patient. Thirty-two subjects (aged 11-61 years) underwent combined xenon-enhanced ventilation and iodine-enhanced perfusion DECT. Ventilation, perfusion and morphological information were visually interpreted. Ventilation/perfusion information was classified as mismatch (differing patterns) or match (concordant patterns). Adverse reactions and radiation doses were recorded for each subject. Of 32 patients undergoing xenon-enhanced DECT, six patients reported adverse reactions (shortness of breath, n = 2; mild dizziness, n = 3; limb numbness, n = 1). Twenty-eight of 32 patients could be included into the data analysis. PE was detected in 10/28 patients. PE-related ventilation/perfusion mismatch was found in 17 lung lobes in 8/10 patients and matched ventilation/perfusion was detected in 2 patients. Eighteen patients had no PE. In this group, there was no case of a ventilation/perfusion mismatch. Matched ventilation/perfusion impairment was seen in one patient. The overall radiation dose from two DECT acquisitions was 4.8 +/- 1.4 mSv (range 2.7-7.5 mSv). DECT lung ventilation/perfusion imaging is feasible and can visualise ventilation/perfusion match or mismatch in patients with suspected PE. aEuro cent Combined dual-energy CT lung ventilation/perfusion imaging is feasible. aEuro cent Combined dual-energy CT ventilation/perfusion imaging provides lung morphological and functional information. aEuro cent Dual-energy CT can demonstrate ventilation/perfusion mismatch in patients with pulmonary embolism.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据