期刊
EUROPEAN RADIOLOGY
卷 24, 期 1, 页码 223-231出版社
SPRINGER
DOI: 10.1007/s00330-013-3002-z
关键词
Diffusion-weighted MR imaging; Intravoxel incoherent motion theory; Contrast-enhanced MR imaging; Head and neck tumours; Differential diagnosis
Objectives We evaluated the combined use of intravoxel incoherent motion (IVIM) and time-signal intensity curve (TIC) analyses to diagnose head and neck tumours. Methods We compared perfusion-related parameters (PP) and molecular diffusion values (D) determined from IVIM theory and TIC profiles among 92 tumours with different histologies. Results IVIM parameters (f and D values) and TIC profiles in combination were distinct among the different types of head and neck tumours, including squamous cell carcinomas (SCCs), lymphomas, malignant salivary gland tumours, Warthin's tumours, pleomorphic adenomas and schwannomas. A multiparametric approach using both IVIM parameters and TIC profiles differentiated between benign and malignant tumours with 97 % accuracy and diagnosed different tumour types with 89 % accuracy. Conclusions Combined use of IVIM parameters and TIC profiles has high efficacy in diagnosing head and neck tumours. Key points Head and neck tumours have wide MR perfusion/diffusion properties. Dynamic contrast-enhanced (DCE) MR imaging can characterise tumour perfusion (TIC analysis). Intravoxel incoherent motion (IVIM) imaging can provide diffusion and perfusion properties. However, IVIM or DCE imaging alone is insufficient for diagnosing head/neck tumours. Multiparametric approach using both IVIM and TIC profiles can facilitate the diagnosis.
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