期刊
EUROPEAN POLYMER JOURNAL
卷 47, 期 10, 页码 1893-1902出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eurpolymj.2011.07.024
关键词
Transdermal drug delivery system; Electro-responsive; Multi-walled carbon nanotubes; Oxyfluorination; Dispersion stability
The electro-responsive transdermal drug delivery system was prepared by electrospinning of poly(vinyl alcohol)/poly(acrylic acid)/multi-walled carbon nanotubes (MWCNTs) nano-composites. The surface modification of MWCNTs was carried out by oxyfluorination to introduce the functional groups on the hydrophobic MWCNTs. The dispersion of MWCNTs and the compatibility with polymer matrices were improved by oxyfluorination. The MWCNT content and oxyfluorination condition played important roles in the swelling and drug release characteristics of nanofibers. The conductivity of nanofibers increased by increasing the content of MWCNTs and performing oxyfluorination with higher oxygen content. Uniform distribution of the oxyfluorinated MWCNTs in the nanofibers was crucial to the electro-responsive swelling and drug releasing behaviors of nanofibers. (C) 2011 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据