期刊
EUROPEAN JOURNAL OF PEDIATRIC SURGERY
卷 24, 期 3, 页码 219-226出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1378150
关键词
regenerative medicine; stem cell; amniotic fluid; mesenchymal stem cells; NEC
资金
- National Institute for Health Research [RP_2014-04-046] Funding Source: researchfish
- Department of Health [RP_2014-04-046] Funding Source: Medline
- National Institutes of Health Research (NIHR) [RP_2014-04-046] Funding Source: National Institutes of Health Research (NIHR)
Regenerative medicine aims to replace, repair, or restore normal function of cells, tissues, and organs that are damaged by disease and holds a promising potential for the treatment of congenital anomalies. Herein, we present an overview of the different stem cell populations and discuss the potentials and most recent updates in stem cell therapy relevant to pediatric surgeons. In particular, we focus on stem cell applications in intestinal regeneration for necrotizing enterocolitis, liver regeneration in biliary atresia and human hepatocyte transplantation for liver failure, and pulmonary regeneration of hypoplastic lungs due to prematurity or congenital diaphragmatic hernia.
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