期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2018, 期 46, 页码 6469-6473出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201801039
关键词
Pyrazolone; Allenamide; Asymmetric catalysis; Chiral phosphoric acid; Heterocycles
资金
- Fundamental Research Funds for the Central Universities [DUT18LAB16]
We describe a new asymmetric allylic alkylation of pyrazolones, in which an all-carbon quaternary stereocenter with broad substrate scope and good enantioselectivity was generated. The asymmetric addition of pyrazolones to allenamides could be carried out under mild conditions in excellent yields with a relatively low catalyst loading. The allylic products with an enamide structure can be easily transformed to the pyrazolones with other functional groups, which provides a new approach for the asymmetric introduction of new functional groups into the pyrazolone skeleton.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据