期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2014, 期 23, 页码 5017-5022出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201402629
关键词
Fluorine; Sulfur; Cyclization; Alkynes; Oxygen heterocycles; Lewis acid catalysis
资金
- National Natural Science Foundation of China [21262016]
- Project of Jiangxi Youth Scientist [20122BCB23012]
- Jiangxi Educational Committee [GJJ12169]
- Visiting Programme of Jiangxi Normal University graduate
- Natural Science Foundation of Jiangxi Province of China [20133ACB20008, 20132BAB203006]
The incorporation of the (trifluoromethyl)thio group into the isocoumarin scaffold through a Lewis-acid-mediated electrophilic cyclization reaction of 2-(2-alkynyl)benzoates with trifluoromethanesulfanylamide is reported. The transformation proceeds well in the presence of BiCl3 and BF3 center dot Et2O under mild conditions to give 4-[(trifluoromethyl)thio]-1H-isochromen-1-ones regioselectively and in good yields.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
