Copper-Catalyzed N- and O-Arylation of Amides: Alternative Approaches to 3,4-Dihydroquinolin-2-ones, Quinolin-2-ones, and 12H-Chromeno[2,3-b]quinolin-12-ones

The efficient syntheses of 3-cyanoquinolin-2-ones, 3-(2-bromobenzyl)-3-cyano-3,4-dihydroquinolin-2-ones, 3-(2-bromobenzyl)quinolin-2-ones, and 12H-chromeno[2,3-b]quinolin-12-ones through copper-catalyzed N- and O-arylation of amides by using readily available 2-bromobenzyl bromides and cyanoacetamides as starting materials were developed.