4.5 Article

Stereoselective Synthesis of Tetrahydroquinolines Through an Imino-Ene Cyclization Reaction

期刊

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2013, 期 5, 页码 952-956

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201201363

关键词

Synthetic methods; Nitrogen heterocycles; Cyclization; Diastereoselectivity; Lewis acids

资金

  1. council of Scientific and Industrial Research (CSIR), New Delhi [01(2332)/09/EMR-II]

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Tetrahydroquinolines have been efficiently synthesized in good yields with excellent stereoselectivity. The reaction between alpha-allylic anilines and aldehydes proceeds through an imino-ene cyclization that is mediated by boron trifluoride-diethyl ether.

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