期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2013, 期 20, 页码 4280-4284出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201300047
关键词
Synthetic methods; Nitrogen heterocycles; Wittig reactions; Domino reactions; Reduction; Lactams
资金
- Department of Science and Technology (DST), New Delhi
- Council for Scientific and Industrial Research (CSIR), New Delhi
- CSIR (New Delhi)
Abstract A convenient and efficient two-step route to 6H-Isoindolo[2,1-a]indol-6-ones has been developed starting from o-nitrobenzaldehydes. The methodology involves Wittig reaction followed by tandem reductive cyclization-lactamization. A series of isoindoloindolones incorporating different substituents on the indole nucleus has been prepared.
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