期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2013, 期 7, 页码 1223-1227出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201201587
关键词
Synthetic methods; Multicomponent reactions; Click chemistry; Nitrogen heterocycles; Fused-ring systems; Copper
资金
- Fund for Scientific Research - Flanders (FWO), Belgium
- University of Leuven (KU Leuven)
- Erasmus Mundus External Cooperation Window (EMECW) (Lot 13)
- EMA2experts (Erasmus Mundus Action 2, Lot 11 Asia: Experts)
A diversity-oriented approach comprising an Ugi 4-component reaction and a copper-catalyzed tandem azide-alkyne cycloaddition/Ullmann C-N coupling is elaborated. The methodology is compatible with various functional groups and allows the construction of triazolo[1,5-a][1,4]benzodiazepinones in good yields.
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