期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2012, 期 3, 页码 576-580出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201101402
关键词
Amino acids; Michael addition; Nitrodienes; Organocatalysis; Thiourea
The primary amine-thiourea based on di-tert-butyl (S)aspartate and (1R,2R)-1,2-diphenylethylene-1,2-diamine has been successfully employed in the difficult Michael reaction between aromatic ketones or acetone with nitrodienes. The high stability and reactivity of the catalyst led to improved reaction conditions. Thus, the desired products were obtained in high to excellent yields (up to 100%) and excellent enantioselectivities (up to 99%) even at elevated temperatures.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据