期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2012, 期 3, 页码 500-508出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201101306
关键词
Natural products; Nanoparticles; Total synthesis; Cycloaddition; Click reaction
资金
- National Natural Science Foundation (NSFC) [21072106]
- Fok Ying Tong Education Foundation [122037]
- Natural Science Foundation of Tianjin (TJNSF) [09JCZDJC21900]
We report the total synthesis of a triazole-epothilone analogue 1. The key step to generate the macrocyclic ring and the triazole ring was to apply Cu2O nanoparticles (Cu2O-NPs) to catalyze the 1,3-dipolar cycloaddition. The conformation of 1 and its bioactivity in MCF cancer cell lines were investigated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
