期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2012, 期 1, 页码 58-61出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201101550
关键词
Fluorine; Alkynes; Copper
资金
- National Natural Science Foundation of China [21072028, 20832008]
An improved method for the efficient copper-mediated trifluoromethylation of terminal alkynes has been developed. This protocol highlights the convenient access to a variety of aryl-substituted trifluoromethylated alkynes by oxidative trifluoromethylation with two equivalents of TMSCF3 at room temperature.
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