期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2010, 期 29, 页码 5619-5632出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201000612
关键词
Carbohydrates; Glycals; Molecular diversity; Template synthesis; Epoxidation
资金
- Ministerio de Ciencia e Innovacion (MICINN) [CTQ2006-15279-C03-02, CTQ2009-10343]
- Comunidad de Madrid [S2009/PPQ-1752]
- Janssen-Cilag SA
Highly functionalized 1-exo-alkylidene-2,3-anhydro-, and 1'-halo-1-exo-alkylidene-2,3-anhydrofuranoses can be prepared in four or five steps, respectively, from D-mannose. These compounds feature a variety of functionalities, including a double bond, an oxirane, an allylic oxirane and (in the case of the 1'-halo derivative) an alkenyl halide. The reactivity of each functionality in these derivatives has been explored, and the usefulness of these substrates has been demonstrated with the preparation of furanose-based carbohydrate templates with up to four sites of molecular diversity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据