期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2010, 期 6, 页码 999-1015出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200900935
关键词
Dynamic kinetic resolution; Transesterification; Enzymes; Alcohols; Amines
资金
- Korea Research Foundation [KRF-2008-314-C00203]
- Korean Ministry of Education
- National Research Foundation of Korea [2008-314-C00203] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Dynamic kinetic resolution (DKR) is an attractive process for the transformation of racemic mixtures into optically active compounds. For successful DKR, efficient racemization is required while the kinetic resolution is proceeding, This Micro-review mainly summarizes the recent developments in the DKR of alcohols and amines, based on metal-catalyzed racemization and enzymatic acylation in a single reaction vessel. Related reactions involving precursors of alcohols and amines Such as ketones, enol acetates, and ketoximes are also described. Reaction conditions are arranged according to racemization catalysts, and substrates employed in the DKR are tabulated. Suggested mechanisms for metal-catalyzed racemizations are also summarized.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据