期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2008, 期 35, 页码 5887-5890出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200800942
关键词
Kinetic resolution; Carboxylic acids; Anhydrides
资金
- Center for Green Photo-Science and Technology
- Ministry of Education, Science Sports and Culture, Japan.
A variety of optically active carboxylic esters were produced by kinetic resolution of racemic carboxylic acids by using achiral alcohols, benzoic anhydrides, and Birman's tetramisole-type catalysts. Bis(alpha-naphthyl)methanol is a very effective reagent for producing the corresponding esters with high ee values in the presence of 4-methoxybenzoic anhydride (PMBA) as the coupling reagent by promotion of benzotetramisole derivatives (BTM, alpha-Np-BTM, and beta-Np-BTM). This protocol directly provides chiral carboxylic esters from free carboxylic acids and achiral alcohols by utilizing a transacylation process to generate the mixed anhydrides from the acid components with benzoic anhydride derivatives in the presence of chiral catalysts. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据