Synthesis of Isoxazolopyridobicyclooxacalix[4]arenes: A New Family of Heteracalixarene Systems

A new family of isoxazolopyridobicyclooxacalix[4]arenes was obtained by reaction of dichloroisoxazolopyridines with phloroglucinol. X-ray crystallography and density functional calculations were used for their structural determination and evaluation of their chemical properties. Their role as metal chelators was studied by mass spectrometry. This new family of heteracalixarenes is of potential interest for host-guest interactions. ( (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)