期刊
EUROPEAN JOURNAL OF NEUROLOGY
卷 21, 期 5, 页码 718-724出版社
WILEY
DOI: 10.1111/ene.12346
关键词
amnesia; female; migraine
资金
- Taiwan National Science Council [98-2314-B-010-019-MY2, NSC 100-2628-E-010-002-MY3]
- Taipei Veterans General Hospital [VGHUST101-G7-1-1, V101C-106, V101E7-003]
- NSC [NSC100-2911-I-008-001]
- Brain Research Center, National Yang-Ming University
- Ministry of Education
Background and purposeThe association between migraine and transient global amnesia (TGA) is not determined. Only two clinic-based studies showed that TGA patients had a higher frequency of migraine history. Our population-based study aimed to investigate whether migraine patients were associated with a higher risk of developing TGA. MethodsPatients with migraine aged 18years were identified from the Taiwan National Health Insurance Research Database between 2005 and 2009. Each migraine patient was randomly matched to one subject without migraine or other headache disorders based on age, sex and cardiovascular comorbidities. Patients with antecedent stroke, epilepsy or TGA were excluded. Both cohorts were followed up until the end of 2010. The incidence rates of TGA were compared and risk factors were identified. ResultsA total of 158301 patients in the migraine cohort and 158301 patients in the matched control cohort were enrolled. During a mean follow-up of 3.0years (range 0-6years), the migraine cohort had a greater risk of developing TGA than the control cohort [7.59 vs. 3.06 per 100000 person-years, incidence rate ratio (IRR)=2.48, P=0.002]. Compared with the matched cohort, only female migraine patients aged 40-60years showed a significantly higher risk of TGA [IRR=3.18 (1.31-8.82), P=0.005]. Of note, the incidence rates did not differ between migraine patients with and without aura. ConclusionsThis population-based study demonstrates that migraine is associated with an increased risk of TGA, particularly in female patients aged 40-60years.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据