期刊
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
卷 44, 期 10, 页码 3880-3888出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2009.04.021
关键词
Telomere; G-quadruplex ligand; 4,5-Disubstituted acridine
资金
- Yang Ji Chemicals Ltd.
- CNRS
- University of Reims
Several 4,5-bis(dialkylaminoalkyl)-substituted acridines have been prepared starting from acridine and their telomeric G-quadruplex stabilizing properties were evaluated using FRET melting and TRAP (Telomerase Repeat Amplification Protocol Assay) experiments. (C) 2009 Elsevier Masson SAS. All rights reserved.
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