Transient aplastic anemia in Down's syndrome - A rare association

The association of Down's syndrome with aplastic anemia is extremely rare with only six such cases reported in world literature. Herein, we report a child of Down's syndrome with pancytopenia and hypocellular marrow. There was associated hypothyroidism and the pancytopenia resolved with thyroxine treatment. The child made uneventful recovery. (C) 2011 Elsevier Masson SAS. All rights reserved.