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Connexin 43 Signaling Enhances the Generation of Foxp3+ Regulatory T Cells
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Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)
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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
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Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells
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miR-142-3p restricts cAMP production in CD4+CD25- T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA
Bo Huang et al.
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T Cell Adhesion Primes Antigen Receptor-Induced Calcium Responses through a Transient Rise in Adenosine 3′,5′-Cyclic Monophosphate
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Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells
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Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
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Inhibition of cAMP Degradation Improves Regulatory T Cell-Mediated Suppression
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The Cyclic AMP Response Element Modulator α Suppresses CD86 Expression and APC Function
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Nonfunctional Regulatory T Cells and Defective Control of Th2 Cytokine Production in Natural Scurfy Mutant Mice
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Rapid Regulatory T-Cell Response Prevents Cytokine Storm in CD28 Superagonist Treated Mice
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T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
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Regulatory T cells and immune tolerance
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Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target
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The Foxp3(+) regulatory T cell: a jack of all trades, master of regulation
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CTLA-4 control over Foxp3+ regulatory T cell function
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Regulation of the NFAT pathway discriminates CD4+CD25+ regulatory T cells from CD4+CD25- helper T cells
Tina L. Sumpter et al.
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CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression:: a role for DNA methylation
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Cyclic adenosine monophosphate is a key component of regulatory T cell mediated suppression
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
Silvia Deaglio et al.
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Frontline: ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells
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EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
Alexander Marson et al.
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Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
Ye Zheng et al.
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Foxp3-dependent programme of regulatory T-cell differentiation
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Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
Katharina Lahl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
Ganesh Suntharalingam et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
CELL (2006)
G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo
Wiebke Hansen et al.
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Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
QZ Tang et al.
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Developmental regulation of Foxp3 expression during ontogeny
JD Fontenot et al.
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Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis
N Beyersdorf et al.
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Regulatory T cells and autoimmune disease
S Paust et al.
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CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
XG Tai et al.
NATURE IMMUNOLOGY (2005)
NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells
T Bopp et al.
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Regulation of immune cells by local. tissue oxygen tension: Hif1 alpha and adenosine receptors
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Tolerance, not immunity, crucially depends on IL-2
TR Malek et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Cyclic adenosine 5'-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus
VC Kyttaris et al.
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The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes
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Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
S Paust et al.
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Cutting edge:: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
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TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling
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Modulation of tryptophan catabolism by regulatory T cells
F Fallarino et al.
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Transcriptional regulation by calcium, calcineurin, and NFAT
PG Hogan et al.
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Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
Cyclic adenosine 5′-monophosphate and calcium induce CD152 (CTLA-4) up-regulation in resting CD4+ T lymphocytes
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Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo
MA Gavin et al.
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Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
CC Caldwell et al.
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Mitogen-activated protein kinase phosphorylates and targets inducible cAMP early repressor to ubiquitin-mediated destruction
G Yehia et al.
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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation
S Read et al.
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Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
T Takahashi et al.
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