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注意：仅列出部分参考文献，下载原文获取全部文献信息。The costimulatory role of TIM molecules
Roselynn Rodriguez-Manzanet et al.
IMMUNOLOGICAL REVIEWS (2009)
Bimodal regulation of T cell-mediated immune responses by TIM-4
Masayuki Mizui et al.
INTERNATIONAL IMMUNOLOGY (2008)
Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice
Nicolas Degauque et al.
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Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
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New roles for TIM family members in immune regulation
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Th17: the third member of the effector T cell trilogy
Estelle Bettelli et al.
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TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
Mandy J. McGeachy et al.
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TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells
Norimoto Kobayashi et al.
IMMUNITY (2007)
Identification of Tim4 as a phosphatidylserine receptor
Masanori Miyanishi et al.
NATURE (2007)
Dynamics of antigen-specific regulatory T-cells in the context of autoimmunity
Thomas Korn et al.
SEMINARS IN IMMUNOLOGY (2007)
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
Sheng Xiao et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
Susumu Nakae et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
Thomas Korn et al.
NATURE MEDICINE (2007)
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals
Lauri L. Binne et al.
JOURNAL OF IMMUNOLOGY (2007)
CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE
Samantha L. Bailey et al.
NATURE IMMUNOLOGY (2007)
T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation
AJ de Souza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Tim-2 regulates T helper type 2 responses and autoimmunity
S Chakravarti et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The TIM gene family regulates autoimmune and allergic diseases
JH Meyers et al.
TRENDS IN MOLECULAR MEDICINE (2005)
Expression of T cell immunoglobulin- and mucin-domain-containing molecules-1 and-3 (TIM-1 and -3) in the rat nervous and immune systems
AW Gielen et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
TIM-1 induces T cell activation and inhibits the development of peripheral tolerance
SE Umetsu et al.
NATURE IMMUNOLOGY (2005)
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation
JH Meyers et al.
NATURE IMMUNOLOGY (2005)
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
EJ McMahon et al.
NATURE MEDICINE (2005)
TGF-β1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
K Nakamura et al.
JOURNAL OF IMMUNOLOGY (2004)
Myelin proteolipid protein-specific CD4+ CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis
J Reddy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-β2-deficient mice:: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system
GX Zhang et al.
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A blast from the past: Clearance of apoptotic cells regulates immune responses
J Savill et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
WK Han et al.
KIDNEY INTERNATIONAL (2002)
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
JJ McIntire et al.
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Brain dendritic cells and macrophages/microglia in central nervous system inflammation
HG Fischer et al.
JOURNAL OF IMMUNOLOGY (2001)
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