期刊
EUROPEAN JOURNAL OF IMMUNOLOGY
卷 40, 期 3, 页码 627-630出版社
WILEY
DOI: 10.1002/eji.200940160
关键词
Apoptosis; Inflammation; Macrophages
类别
资金
- Ligue Nationale contre le Cancer
- Agence Nationale pour la Recherche (ANR)
- European Commission
- Fondation pour la Recherche Medicale (FRM)
- Institut National du Cancer (INCa)
- Canceropole Ile-de-France
- INSERM
- Apo-Sys
The term pyroptosis was originally introduced to describe a particular form of cell death in macrophages, which is induced by bacterial infection, is accompanied by caspase-1 activation and hence leads to the release of pyrogenic interleukins; however, it is still controversial whether pyroptosis which can also be triggered by non-bacterial pathological stimuli - truly represents a cell death modality on its own or whether it constitutes a special case of apoptosis or necrosis.
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