4.5 Article

Pyroptosis - a cell death modality of its kind?

期刊

EUROPEAN JOURNAL OF IMMUNOLOGY
卷 40, 期 3, 页码 627-630

出版社

WILEY
DOI: 10.1002/eji.200940160

关键词

Apoptosis; Inflammation; Macrophages

资金

  1. Ligue Nationale contre le Cancer
  2. Agence Nationale pour la Recherche (ANR)
  3. European Commission
  4. Fondation pour la Recherche Medicale (FRM)
  5. Institut National du Cancer (INCa)
  6. Canceropole Ile-de-France
  7. INSERM
  8. Apo-Sys

向作者/读者索取更多资源

The term pyroptosis was originally introduced to describe a particular form of cell death in macrophages, which is induced by bacterial infection, is accompanied by caspase-1 activation and hence leads to the release of pyrogenic interleukins; however, it is still controversial whether pyroptosis which can also be triggered by non-bacterial pathological stimuli - truly represents a cell death modality on its own or whether it constitutes a special case of apoptosis or necrosis.

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