期刊
EUROPEAN JOURNAL OF IMMUNOLOGY
卷 39, 期 3, 页码 667-669出版社
WILEY
DOI: 10.1002/eji.200839088
关键词
Destruction; Diseases; IL 17; Inflammation; Th17
类别
资金
- Hospices Civils de Lyon
- Region Rhone-Alpes
The discovery of 11,47 and of the Th17 pathway has been a step in the classification of human diseases. Th17 targeting appears rather straightforward in diseases associated with inflammation and matrix destruction, such as rheumatoid arthritis, psoriasis, and Crohn's disease. In other conditions where IL-17 is expressed and Th17 activated, it is unclear whether this is a primary or secondary event, making the use of Th17 inhibitors less obvious.
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