期刊
EUROPEAN JOURNAL OF IMMUNOLOGY
卷 38, 期 4, 页码 921-924出版社
WILEY-BLACKWELL
DOI: 10.1002/eji.200738104
关键词
Autoimmunity; Human; Regulatory T cell
类别
资金
- National Institutes of Health [U19AI070352, P01AI39671]
- National Multiple Sclerosis Society [RG3825A1]
- 2004 Federation of Clinical Immunology Society Centers of Excellence Amgen Award
CD4(+)CD25(+) regulatory T cells (Treg) appear to be critical in regulating immune responses to self-antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mechanism of action remains unknown. In this review, we discuss the phenotype of human natural Treg, their functional mechanism, and their role in autoimmune disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据