期刊
EUROPEAN JOURNAL OF IMMUNOLOGY
卷 38, 期 4, 页码 928-930出版社
WILEY-BLACKWELL
DOI: 10.1002/eji.200838147
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资金
- Young Scientists [17689021]
- Ministry of Education, Sports and Culture of Japan [19059014]
- Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation (NIBIO)
- Grants-in-Aid for Scientific Research [19059014, 17689021] Funding Source: KAKEN
It has been postulated that expression of the transcription factor Foxp3 specifically identifies the regulatory T cell (Treg) lineage and it acts as its master regulator or lineage specification factor. However, emerging evidence challenges these views and suggests that the Treg lineage may be determined by a higher-order regulatory process that ensures stable and high levels Foxp3 expression.
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