Time to positivity of follow-up blood cultures in patients with persistent Staphylococcus aureus bacteremia

We investigated the clinical usefulness of time to blood culture positivity (TTP) of follow-up positive blood cultures (FUPBC) in patients with persistent Staphylococcus aureus bacteremia (SAB). Of the patients who did not have resolution of SAB after primary therapeutic intervention (PTI), patients who had decreases in TTP of FUPBC after PTI more frequently experienced 30-day mortality or secondary foci of infection than those who did not have decrease in TTP (83.3% vs. 28.6%; p = 0.005).