期刊
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
卷 30, 期 3, 页码 303-305出版社
SPRINGER
DOI: 10.1007/s10096-010-1103-z
关键词
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资金
- Research and Development Program of Science & Technology in Zhejiang of China [2008 C33026]
- Zhejiang Medicine Hygiene Science Research [2009A098]
As a principle receptor to beta-glucan in the Candida albicans cell wall, Dectin-1 performs recognition specifically and its mechanisms are diverse in different situations. With a view to developing certain antifungal targeted drugs, this review provides new insights into the novel immune signaling pathways induced by Dectin-1, especially the novel understandings of CARD9 in the Syk-dependent NF-kappa B pathway, and of Raf-1 in the Syk-independent NF-kappa B signaling pathway.
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