期刊
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
卷 42, 期 3, 页码 420-429出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ejcts/ezs081
关键词
Postoperative complications; Thoracotomy; Thoracic surgery; Video-assisted; Early detection of cancer; Lung neoplasms
资金
- Zorg Onderzoek Nederland-Medische Wetenschappen (ZonMw)
- KWF Kankerbestrijding
- Stichting Centraal Fonds Reserves van Voormalig Vrijwillige Ziekenfondsverzekeringen (RvvZ)
- G. Ph. Verhagen Foundation
- Rotterdam Oncologic Thoracic Study Group (ROTS)
- Erasmus Trust Fund
- Stichting tegen Kanker (Belgium)
- Vlaamse Liga tegen Kanker
- LOGO Leuven
- LOGO Hageland
To assess the complication rate in participants of the screen arm of the NELSON lung cancer screening trial who underwent surgical resection and to investigate, based on a literature review, whether the complication rate, length of hospital stay, re-thoracotomy and mortality rates after a surgical procedure were different from those of the non-screening series, taking co-morbidity into account. Between April 2004 and December 2008, 198 subjects underwent thoracic surgery. Co-morbid conditions were retrieved from the medical records. Postoperative complications were classified as minor and major. In total, 182 thoracotomies, 5 thoracotomies after video-assisted thoracoscopic surgery (VATS) and 11 VATS procedures were performed. In these patients, 36% had chronic obstructive lung disease, 16% coronary artery disease, 14% diabetes mellitus and 11% peripheral vascular disease. Following thoracotomy, 47% (88/187) had >= 1 minor (7-57% in literature) and 10% (18/187) >= 1 major complication (2-26% in literature); following VATS, 38% (6/16) had >= 1 minor complication, but no major complications. Seventeen per cent (3/18) of major complications and 21% (20/96) of minor complications were seen in subjects operated for benign disease. The re-thoracotomy rate was 3% and there was no 30-day mortality after thoracotomy or VATS (0-8.3% in literature). The mortality rate of 0% after surgical procedures is low when compared with the non-screening series (0-8.3%); the rate of complications (53%) is within range when compared with the non-screening series (8.5-58%). In conclusion, mortality rates after surgical procedures are lower in the NELSON lung cancer screening trial than those in the non-screening series. The rate of complications is within the same range as in the non-screening series. Trial registration number: ISR CTN 63545820.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据