期刊
EUROPEAN HEART JOURNAL
卷 30, 期 6, 页码 671-678出版社
OXFORD UNIV PRESS
DOI: 10.1093/eurheartj/ehn541
关键词
Heart failure; Mortality; Gender; Ischaemic; Non-ischaemic
资金
- The Swedish Research Council
- The Swedish Council for Working Life and Social Research
- The Swedish Heart and Lung Foundation
- Goteborg and Southern Bohus County
- The Goteborg Medical Society
- The Cardiology Research Foundation of the Department of Medicine, Sahlgrenska University Hospital/Ostra
To investigate gender-specific trends in long-term mortality in patients hospitalized for heart failure (HF). The Swedish hospital discharge and cause-specific death registers were used to calculate age- and gender-specific trends for long-term prognosis in patients hospitalized with a principal diagnosis of HF from 1987 to 2003. Mortality decreased, mainly during 1987-95, with no further decrease after 2001. Survival in men improved more than in women (P-value for interaction 0.0003), particularly among patients aged < 65 years (P-value for interaction: age, gender, and year of hospitalization 0.0003) and more for patients with ischaemic when compared with non-ischaemic HF (P-value for interaction < 0.0001). Among men < 65 years, the hazard ratio (HR) of dying within 3 years after discharge was 0.40 (95% confidence interval 0.36-0.45) during 1999-2001 when compared with 1987-89. The corresponding HR for women was 0.58 (0.48-0.69). For those discharged during 1999-2001, almost 20% of the patients aged 35-64 years and 40% of those aged 65-84 years died within 3 years. Long-term mortality in HF in Sweden decreased more for men than for women and more for ischaemic than non-ischaemic HF. There was no further decrease after 2001. Long-term mortality after a first hospitalization remained high.
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