期刊
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
卷 21, 期 10, 页码 583-589出版社
SPRINGER
DOI: 10.1007/s00787-012-0298-1
关键词
Extremely premature infant; Extremely low birthweight; SDQ; Mental health; Follow-up
资金
- Norwegian Foundation for Health and Rehabilitation through The Unexpected Child Death Society of Norway
- Research Council of Norway
- Helse Vest Hospital Trust
- Uni Health Center for Child and Adolescent Mental Health
The objective of this study was to compare mental health at 5 years in children born extremely preterm with a reference group, and assess associations between functional abilities and mental health within the preterm group. In a national Norwegian cohort with gestational age 22-27 weeks or birthweight 500-999 g, mental health was assessed with the Strengths and Difficulties Questionnaire (SDQ), cognitive function with the Wechsler Preschool and Primary Scale of Intelligence-Revised (WPPSI-R), motor function with the Movement Assessment Battery for children (ABC-test) and severity of cerebral palsy (CP) with the Gross Motor Function Classification for CP (GMFCS). Neurodevelopmental disabilities (NDD) were described as mild and moderate/severe. SDQ of the preterm children was compared with that of an unselected reference group. SDQ sub-scores a parts per thousand yen90th percentile of the reference group were defined as a mental health problem and a Total Difficulties Score a parts per thousand yen90th percentile (TDS90) as suggestive of psychiatric disorder. Of 361 eligible preterm children, parents completed SDQ for 255 (71 %). 97 (38 %) had TDS90 compared to 116 (11 %) of the reference group (OR 5.1; 95 % CI 3.7-7.1). For the preterms, the rate of TDS90 was higher for those with moderate/severe NDD (27/37 vs. 27/116, adjusted OR 8.0; 95 % CI 3.2-19, and mild NDD 43/102 [adjusted OR 2.2 (1.2-4.1)]. For preterms with no NDD, TDS90 was more common than for the reference group (27/116 vs. 116/1,089, OR 2.5; 95 % CI 1.6-4.1). Extreme prematurity was associated with increased risk of later mental health problems, particularly if they had other functional impairments.
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