期刊
EUKARYOTIC CELL
卷 7, 期 9, 页码 1611-1615出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/EC.00458-07
关键词
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资金
- NIH [R21 RR20355, R01 GM71007, R01 GM66303]
- William Keck Foundation
- NIH/NCRR [P20 RR16459]
- [GM F32 072341]
The Man alpha 1,3(Xyl beta 1,2)Man alpha structural motif is common to both capsular polysaccharides of Cryptococcus neoformans and to cryptococcal glycosphingolipids. Comparative analysis of glycosphingolipid structural profiles in wild-type and mutant strains showed that the Xyl beta 1,2-transferase (Cxt1p) that participates in capsular polysaccharide biosynthesis is also the sole transferase responsible for adding xylose to C. neoformans glycosphingolipids.
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