Creating morphable logic gates using logical stochastic resonance in an engineered gene network

The idea of Logical Stochastic Resonance is adapted and applied to an autoregulatory gene network in the bacteriophage lambda. This biological logic gate can emulate or morph the AND and OR gates, through varying internal system parameters, in a noisy background. Such logic gates afford intriguing possibilities in the realization of engineered genetic networks, in which the function of the gate can be changed after the network has been assembled: this allows a single gene network to be used for many different applications in the emerging field of synthetic biology. Copyright (C) EPLA, 2011