期刊
EPILEPSY & BEHAVIOR
卷 14, 期 1, 页码 121-124出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yebeh.2008.08.014
关键词
Cognitive functions; Depression; Aggression; Personality traits; Generalized tonic-clonic epilepsy; Partial epilepsy
Objective: This study was designed to assess cognitive function, mood, aggression, and personality traits among adult men with idiopathic epilepsy. Methods: Seventy-one male patients with idiopathic epilepsy were recruited from the Outpatient epilepsy clinic of Assuit University hospitals. Another 58 subjects matched with respect to age, sex, and socioeconomic status formed the control group. For each participant, a complete medical history was obtained, and clinical examination, EEC, and psychometric evaluation were performed. For the psychometric evaluation, we used the Stanford-Binet test (fourth edition) to assess cognitive function, the Beck Depression Inventory to assess symptoms of depression, the Aggressive Behavior Scale, and the Eysenck Personality Questionnaire. Results: Patients with epilepsy reported highly significant impairment in all cognitive measures and higher scores on depressive symptoms, aggressive behavior, and most personality traits compared with controls. Early age at onset, prolonged duration of illness, increased frequency of seizures, and history of status epilepticus were significantly negatively correlated with some of the cognitive function subscales. Conclusion: Epilepsy itself and epilepsy-related factors are associated with cognitive function deterioration, depression, aggression, and some abnormal personality traits. (C) 2008 Elsevier Inc. All rights reserved.
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