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Xiaochao Ma et al.
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Christine Naspinski et al.
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N. A. G. Santos et al.
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Ping Kang et al.
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Lukas Cerveny et al.
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R. P. Meyer et al.
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Nicola Marchi et al.
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Analysis of carbamazepine and its active metabolite, carbamazepine-10,11-epoxide, in human plasma using high-performance liquid chromatography
Eun kyung Oh et al.
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S. Joshua Langmade et al.
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Dhananjay Pal et al.
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B Rambeck et al.
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Drug resistance in brain diseases and the role of drug efflux transporters
W Löscher et al.
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The NMDA receptor NR2B subunit contributes to epileptogenesis in human cortical dysplasia
G Möddel et al.
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Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy
E Aronica et al.
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Terminology and classification of the cortical dysplasias
A Palmini et al.
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H Potschka et al.
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E van Vliet et al.
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Nicola Marchi et al.
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G Gervasini et al.
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HR Dhaini et al.
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M Marroni et al.
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P Bittigau et al.
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Interaction of cytochrome P450 3A inhibitors with P-glycoprotein
K Yasuda et al.
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P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier:: evidence from microdialysis experiments in rats
H Potschka et al.
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SM Dombrowski et al.
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W Burman et al.
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W Xie et al.
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GK Dresser et al.
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