期刊
EPILEPSIA
卷 52, 期 9, 页码 E106-E108出版社
WILEY
DOI: 10.1111/j.1528-1167.2011.03124.x
关键词
Ganglioglioma; Cortical dysplasia; Epilepsy; Tumor
资金
- NINDS NIH HHS [R01 NS056222, T32 NS007413] Funding Source: Medline
We report the case of a child who presented at 3 months of age with complex partial seizures, a linear facial nevus, and magnetic resonance imaging (MRI) showing delayed myelination and thickened cortex in the left temporal, parietal, and occipital regions. A repeat 3Tesla MRI scan with and without contrast at 6 months again showed cortical dysplasia of the left hemisphere. No other abnormalities were seen. A third scan at 3 years 6 months showed a 2.5 cm, round, hyperintense lesion on both T-2 and T-1 sequences. The lesion and surrounding dysplastic cortex were resected. Palmini grade IIA dysplasia and a ganglioglioma were diagnosed. These findings suggest that cellular components of cortical dysplasias have oncogenic potential.
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