期刊
EPIGENETICS
卷 9, 期 1, 页码 27-36出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/epi.26942
关键词
transcriptional activation; saRNA; RNAa; non-coding RNA; eRNA; lincRNA; epigenetic; enhancer
资金
- NIH [GM064701, CA131301, AG033921, CA157749]
The regulation of gene expression by non-coding RNAs (ncRNAs) has become a new paradigm in biology. RNA-mediated gene silencing pathways have been studied extensively, revealing diverse epigenetic and posttranscriptional mechanisms. In contrast, the roles of ncRNAs in activating gene expression remains poorly understood. In this review, we summarize the current knowledge of gene activation by small RNAs, long non-coding RNAs, and enhancer-derived RNAs, with an emphasis on epigenetic mechanisms.
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