相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Changes in MicroRNA Expression Contribute to Pancreatic β-Cell Dysfunction in Prediabetic NOD Mice
Elodie Roggli et al.
DIABETES (2012)
Glucose-Mediated Repression of Menin Promotes Pancreatic β-Cell Proliferation
Hongli Zhang et al.
ENDOCRINOLOGY (2012)
MicroRNAs in metabolism and metabolic disorders
Veerle Rottiers et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study
Lei Kong et al.
ACTA DIABETOLOGICA (2011)
Implications of genome wide association studies for the understanding of type 2 diabetes pathophysiology
John R. Petrie et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Control of Pancreatic β Cell Regeneration by Glucose Metabolism
Shay Porat et al.
CELL METABOLISM (2011)
Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx
Sangeeta Dhawan et al.
DEVELOPMENTAL CELL (2011)
Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity
Keith M. Godfrey et al.
DIABETES (2011)
Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the intrauterine growth retarded rat
S. E. Pinney et al.
DIABETOLOGIA (2011)
miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors
Tal Melkman-Zehavi et al.
EMBO JOURNAL (2011)
Hypermethylation of Hepatic Glucokinase and L-Type Pyruvate Kinase Promoters in High-Fat Diet-Induced Obese Rats
Minghong Jiang et al.
ENDOCRINOLOGY (2011)
Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets
Deepti Ramachandran et al.
FEBS JOURNAL (2011)
miR-29a and miR-29b Contribute to Pancreatic β-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)
Timothy J. Pullen et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Over-expression of miR375 reduces glucose-induced insulin secretion in Nit-1 cells
Hua-Qiang Xia et al.
MOLECULAR BIOLOGY REPORTS (2011)
ISLET AMYLOID POLYPEPTIDE, ISLET AMYLOID, AND DIABETES MELLITUS
Per Westermark et al.
PHYSIOLOGICAL REVIEWS (2011)
Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat
Jonathan Lou S. Esguerra et al.
PLOS ONE (2011)
Diabetes mellitus, a microRNA-related disease?
Claudiane Guay et al.
TRANSLATIONAL RESEARCH (2011)
Adipokines in inflammation and metabolic disease
Noriyuki Ouchi et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Type 2 diabetes as an inflammatory disease
Marc Y. Donath et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Glucolipotoxicity of the pancreatic beta cell
Vincent Poitout et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic β-Cells
Elodie Roggli et al.
DIABETES (2010)
Histone methyltransferases: regulation of transcription and contribution to human disease
Keisuke Nimura et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2010)
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1 beta in type 2 diabetes
Seth L. Masters et al.
NATURE IMMUNOLOGY (2010)
An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus
Chirag J. Patel et al.
PLOS ONE (2010)
Oxidative stress and beta-cell dysfunction
Gisela Drews et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
Expansion of beta-cell mass in response to pregnancy
Sebastian Rieck et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han Chinese
Fuu-Jen Tsai et al.
PLOS GENETICS (2010)
The role of epigenetics in aging and age-related diseases
Vincenzo Calvanese et al.
AGEING RESEARCH REVIEWS (2009)
Histone deacetylases: salesmen and customers in the post-translational modification market
Andre Brandl et al.
BIOLOGY OF THE CELL (2009)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
Age-Dependent Decline in beta-Cell Proliferation Restricts the Capacity of beta-Cell Regeneration in Mice
Shuen-Ing Tschen et al.
DIABETES (2009)
Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes
Charlotte Ling et al.
DIABETES (2009)
Adaptive β-cell Proliferation Is Severely Restricted With Advanced Age
Matthew M. Rankin et al.
DIABETES (2009)
Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease
Douwe Pons et al.
EUROPEAN HEART JOURNAL (2009)
Function of microRNA-375 and microRNA-124a in pancreas and brain
Nadine N. Baroukh et al.
FEBS JOURNAL (2009)
Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
Takeshi Inagaki et al.
GENES TO CELLS (2009)
Most mammalian mRNAs are conserved targets of microRNAs
Robin C. Friedman et al.
GENOME RESEARCH (2009)
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
Elmar W. Tobi et al.
HUMAN MOLECULAR GENETICS (2009)
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
Keisuke Tateishi et al.
NATURE (2009)
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Melanie Bahlo et al.
NATURE GENETICS (2009)
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
Michael Haberland et al.
NATURE REVIEWS GENETICS (2009)
Aberrant Epigenetic Silencing Is Triggered by a Transient Reduction in Gene Expression
Jon A. Oyer et al.
PLOS ONE (2009)
Insulin Gene Expression Is Regulated by DNA Methylation
Akio Kuroda et al.
PLOS ONE (2009)
miR-375 maintains normal pancreatic α- and β-cell mass
Matthew N. Poy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
Mamta Tahiliani et al.
SCIENCE (2009)
Induction of Apoptosis of beta Cells of the Pancreas by Advanced Glycation End-Products, Important Mediators of Chronic Complications of Diabetes Mellitus
Minsu Lim et al.
IMMUNOLOGY OF DIABETES V: FROM BENCH TO BEDSIDE (2008)
Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs
Pascal Lovis et al.
BIOLOGICAL CHEMISTRY (2008)
Oxidative stress, DNA methylation and carcinogenesis
Rodrigo Franco et al.
CANCER LETTERS (2008)
miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic β-cells
Abdelfattah El Ouaamari et al.
DIABETES (2008)
Alterations in microRNA expression contribute to fatty acid-induced pancreatic β-cell dysfunction
Pascal Lovis et al.
DIABETES (2008)
Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential
M. H. Jiang et al.
DIABETOLOGIA (2008)
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
C. Ling et al.
DIABETOLOGIA (2008)
We are what we eat - The link between diet, evolution and non-genetic inheritance
Philip Hunter
EMBO REPORTS (2008)
Chromatin-modifying enzymes as therapeutic targets – Part 1
Brian R Keppler et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2008)
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Bastiaan T. Heijmans et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
MicroRNA expression is required for pancreatic islet cell genesis in the mouse
Francis C. Lynn et al.
DIABETES (2007)
Menin controls growth of pancreatic β-cells in pregnant mice and promotes gestational diabetes mellitus
Satyajit K. Karnik et al.
SCIENCE (2007)
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
Dana C. Dolinoy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development (Publication with Expression of Concern. See vol. 20, 2022)
Wigard P. Kloosterman et al.
PLOS BIOLOGY (2007)
MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic β-cell lines
Nadine Baroukh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Role of metabolic programming in the pathogenesis of β-cell failure in postnatal life
Rebecca A. Simmons
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2007)
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
Richa Saxena et al.
SCIENCE (2007)
Developmental origins of β-cell failure in type 2 diabetes:: The role of epigenetic mechanisms
Rebecca A. Simmons
PEDIATRIC RESEARCH (2007)
Obesity, inflammation, and insulin resistance
Steven E. Shoelson et al.
GASTROENTEROLOGY (2007)
A feat of metabolic proportions: Pdx 1 orchestrates islet development and function in the maintenance of glucose homeostasis
Daniella A. Babu et al.
MOLECULAR GENETICS AND METABOLISM (2007)
PPARs, Obesity, and Inflammation
Rinke Stienstra et al.
PPAR RESEARCH (2007)
Transposable elements and the epigenetic regulation of the genome
R. Keith Slotkin et al.
NATURE REVIEWS GENETICS (2007)
Environmental epigenomics and disease susceptibility
Randy L. Jirtle et al.
NATURE REVIEWS GENETICS (2007)
X-tra! X-tra! News from the mouse X chromosome
Joanne L. Thorvaldsen et al.
DEVELOPMENTAL BIOLOGY (2006)
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
Herbert Tilg et al.
NATURE REVIEWS IMMUNOLOGY (2006)
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells
Valerie Plaisance et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
JHDM2A, a JmjC-containing H3K9 dernethylase, facilitates transcription activation by androgen receptor
Kenichi Yamane et al.
CELL (2006)
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
DC Dolinoy et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2006)
Relationship Between Inflammation, Insulin Resistance and Type 2 Diabetes: 'Cause or Effect'?
Jerry R. Greenfield et al.
CURRENT DIABETES REVIEWS (2006)
Molecular control of cell cycle progression in the pancreatic beta-cell
Irene Cozar-Castellano et al.
ENDOCRINE REVIEWS (2006)
Animal evidence for the transgenerational development of diabetes mellitus
L Aerts et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)
Regulation of pancreatic beta-cell mass
L Bouwens et al.
PHYSIOLOGICAL REVIEWS (2005)
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
WJ Lee et al.
MOLECULAR PHARMACOLOGY (2005)
Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycemia in diabetic NOD mice
WL Suarez-Pinzon et al.
DIABETES (2005)
Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes
JD Wren et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2005)
Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis
M Brissova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
IKK-β links inflammation to obesity-induced insulin resistance
MC Arkan et al.
NATURE MEDICINE (2005)
Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy
PD Taylor et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
A pancreatic islet-specific microRNA regulates insulin secretion
MN Poy et al.
NATURE (2004)
Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand
PJ Willy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The development of beta-cell mass: Recent progress and potential role of GLP-1
DA Stoffers
HORMONE AND METABOLIC RESEARCH (2004)
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin
P Marchetti et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
Y Dor et al.
NATURE (2004)
Predicting aberrant CpG island methylation
FA Feltus et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes:: Potential role of PGC1 and NRF1
ME Patti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
KF Petersen et al.
SCIENCE (2003)
Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat
DA Stoffers et al.
DIABETES (2003)
beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
AE Butler et al.
DIABETES (2003)
Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period
G Kaati et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2002)
The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases β-cell mass in diabetic mice
B Rolin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
Q Wang et al.
DIABETOLOGIA (2002)
Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a
S Torii et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Role of oxidative stress in advanced glycation end product-induced mesangial cell activation
MA Lal et al.
KIDNEY INTERNATIONAL (2002)
Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by mass during the prediabetic expansion of the β-cell period with glucagon-like peptide-1 or exendin-4
C Tourrel et al.
DIABETES (2002)
Interleukin-1 plus γ-interferon-induced pancreatic β-cell dysfunction is mediated by β-cell nitric oxide production
HE Thomas et al.
DIABETES (2002)
DNA methylation patterns and epigenetic memory
A Bird
GENES & DEVELOPMENT (2002)
Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients
H Sakuraba et al.
DIABETOLOGIA (2002)
The hormone resistin links obesity to diabetes
CM Steppan et al.
NATURE (2001)
Genomic imprinting: Parental influence on the genome
W Reik et al.
NATURE REVIEWS GENETICS (2001)