期刊
EPIGENETICS
卷 4, 期 3, 页码 139-143出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/epi.4.3.8484
关键词
histone; acetylation; bromodomain; transcription; acetyltransferase
资金
- Canadian Institutes of Health Research
- Canadian Institutes of Health Research New Investigator
- Michael Smith Foundation for Health Research
Transcriptionally active DNA is packaged with histones that are post-translationally acetylated on multiple lysines within their amino termini. While the majority of this acetylation is limited to the promoters of genes, acetylated histones are also found throughout transcribed units. Over the last decade we have uncovered many of the pathways involved in directing histone acetylation to active genes. This review will summarize much of this groundbreaking research as well as discuss some of the outcomes of this important protein post-translational modification.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据