期刊
EPIDEMIOLOGY AND INFECTION
卷 143, 期 9, 页码 1826-1832出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268814003264
关键词
Avian influenza A(H7N9) virus; case-control study; human infection; risk factor
资金
- National Science and Technology Supporting Programme [KJYJ-2013-01-05]
- Joint Research Project of Shanghai Municipal Avian Influenza A(H7N9) Prevention and Control [2013QLG008]
- Constructing Programme of Shanghai Municipal Public Health Key Discipline [12GWZX0101]
The first human infection with avian influenza A(H7N9) virus was reported in Shanghai, China in March 2013. An additional 32 cases of human H7N9 infection were identified in the following months from March to April 2013 in Shanghai. Here we conducted a case-control study of the patients with H7N9 infection (n = 25) using controls matched by age, sex, and residence to determine risk factors for H7N9 infection. Our findings suggest that chronic disease and frequency of visiting a live poultry market (>10 times, or 1-9 times during the 2 weeks before illness onset) were likely to be significantly associated with H7N9 infection, with the odds ratios being 4.07 [95% confidence interval (CI) 1.32 12.56], 10.61 (95% CI 1.85 60.74), and 3.76 (95% CI 1.31-10.79), respectively. Effective strategies for live poultry market control should be reinforced and ongoing education of the public is warranted to promote behavioural changes that can help to eliminate direct or indirect contact with influenza A(H7N9) virus.
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