期刊
EPIDEMIOLOGY AND INFECTION
卷 142, 期 12, 页码 2616-2623出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268814000041
关键词
Hepatitis C virus; HIV/HCV co-infection; human immunodeficiency virus; risk factors
资金
- Brazilian Ministry of Health
- Secretaria de Vigilancia em Saude (Department of Health Surveillance)
- Programa Nacional de Doencas Sexualmente Transmissiveis e Aids (MS/SVS/PN-DST/AIDS Brazilian Program of Sexually Transmitted Diseases and AIDS - Cooperation Term), through the International Technical Cooperation Project [282/07, AD/BRA/03/H34]
- Financiadora de Estudos e Projetos (FINEP - Financial Support Organization for Research and Projects)
- Simbios Biotecnologia (FINEP/FULBRA/LDM - Simbios Biotechnology - Acao Transversal) [0.1.07.0102.00]
We studied hepatitis C virus (HCV) prevalence and risk factors for HCV infection in a sample of Brazilian HIV-positive patients. A cross-sectional study was conducted with 580 HIV-positive patients from a specialized HIV/AIDS diagnosis and treatment centre in southern Brazil. All patients were interviewed for socio-demographic and risk factors and tested for HCV antibodies and HCV-RNA detection. A multivariate analysis was performed to identify risk factors for HCV infection. A total of 138 (24%) patients had past or chronic hepatitis C. The following risk factors were associated with HCV infection for each gender: alcohol misuse and injecting drug use in women (P< 0.001) and low educational level, smoking drug use, and injecting drug use in men (P< 0.01). These results suggest that alcohol misuse, low educational level, smoking drug use, and injecting drug use are probable risk factors for HCV infection in HIV-positive patients. This information contributes to an understanding of the epidemiology of HIV/HCV co-infection in Brazil.
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