期刊
EPIDEMIOLOGY AND INFECTION
卷 139, 期 6, 页码 946-954出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268810001998
关键词
Cryptosporidium; epidemiology; infectious disease epidemiology; molecular epidemiology; parasitic disease epidemiology and control
资金
- Irish Research Council for Science, Engineering and Technology
- Health Research Board [GHRA/2006/7]
A cross-sectional study was conducted to investigate risk factors for sporadic Cryptosporidium infection in a paediatric population in Nigeria. Of 692 children, 134 (19.4%) were infected with Cryptosporidium oocysts. Cryptosporidium spp. were identified in 49 positive samples using PCR-restriction fragment length polymorphism and direct sequencing of the glycoprotein60 (GP60) gene. Generalized linear mixed-effects models were used to identify risk factors for all Cryptosporidium infections, as well as for C. hominis and C. parvum both together and separately. Risk factors identified for all Cryptosporidium infections included malaria infection and a lack of Ascaris infection. For C. hominis infections, stunting and younger age were highlighted as risk factors, while stunting and malaria infection were identified as risk factors for C. parvum infection.
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