期刊
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
卷 37, 期 2, 页码 844-849出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.etap.2014.02.015
关键词
Bisphenol A; Mytilus galloprovincialis; Toxicological effects; Metabolomics
资金
- 100 Talents Program of the Chinese Academy of Sciences
- Key Deployment Program of Chinese Academy of Sciences [KZZD-EW-14-03]
Bisphenol A (BPA) is a synthetic compound used in numerous chemicals, such as polycarbonate plastics and epoxy resins, and it can be released into aquatic environment and poses risk on aquatic organisms. In this work, metabolomics was applied to characterize the metabolic responses in mussel Mytilus galloprovincialis exposed to BPA. Our results indicated that the gonad of female mussel was sensitive to BPA exposures (1 and 10 mu g/L) for one month. However, no significant metabolic responses were observed in male mussel gonads exposed to these two concentrations of BPA. Overall, this limited study suggested that the gender differences should be considered in marine ecotoxicology. (C) 2014 Elsevier B.V. All rights reserved.
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