期刊
ACS NANO
卷 9, 期 12, 页码 12344-12348出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.5b05629
关键词
latent fingerprints; colorimetric imaging; photoacoustic imaging; block copolymer; gold nanoparticles
类别
资金
- Shenzhen University
- University of Maryland
- National Natural Science Foundation of China [81401465, 51573096, 11204021, 81272987]
- National Science Foundation [CHE-1505839]
- Intramural Research Program (IRP) of the NIBIB/NIH
There is a high demand on a simple, rapid, accurate, user-friendly, cost-effective, and nondestructive universal method for latent fingerprint (LFP) detection. Herein, we describe a combination imaging strategy for LFP visualization with high resolution using poly(styrene-alt-maleic anhydride)-b-polystyrene (PSMA-b-PS) functionalized gold nanoparticles (GNPs). This general approach integrates the merits of both colorimetric imaging and photoacoustic imaging. In comparison with the previous methods, our strategy is single-step and does not require the signal amplification by silver staining. The PSMA-b-PS functionalized GNPs have good stability, tunable color, and high affinity for universal secretions (proteins/polypeptides/amino acids), which makes our approach general and flexible for visualizing LFPs on different substrates (presumably with different colors) and from different people. Moreover, the unique optical property of GNPs enables the photoacoustic imaging of GNPs-deposited LFPs with high resolution. This allows observation of level 3 hyperfine features of LFPs such as the pores and ridge contours by photoacoustic imaging. This technique can potentially be used to identify chemicals within LFP residues. We believe that this dual-modality-imaging of LFPs will find widespread use in forensic investigations and medical diagnostics.
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