期刊
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 22, 期 4, 页码 2566-2573出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s11356-014-3497-0
关键词
Ecotoxicity; Flubendazole; Fenbendazole; Aquatic species; Anthelmintic drugs; Benzimidazoles
资金
- German Academic Exchange Service (DAAD)
- National Science Centre, Poland [DEC-2011/03/B/NZ8/03009]
- European Social Fund
Flubendazole (FLU) and fenbendazole (FEN) belong to benzimidazoles-pharmaceuticals widely used in veterinary and human medicine for the treatment of intestinal parasites as well as for the treatment of systemic worm infections. In recent years, usage of these drugs increased, which resulted in a larger contamination of the environment and possible negative effects on biota. Hence, in our research, we investigated an aquatic ecotoxicity of these pharmaceuticals towards: marine bacteria (Vibrio fischeri), green algae (Scenedesmus vacuolatus), duckweed (Lemna minor) and crustacean (Daphnia magna). Ecotoxicity tests were combined with chemical analysis in order to investigate the actual exposure concentration of the compounds used in the experiment as well as to stability and adsorption studies. As a result, study evaluating sensitivity of different aquatic organisms to these compounds and new ecotoxicological data is presented. The strongest negative impact of FLU and FEN was observed to D. magna.
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