期刊
ENVIRONMENTAL SCIENCE & POLICY
卷 27, 期 -, 页码 135-140出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envsci.2012.12.002
关键词
GM crops; Introgression; Hybridization; Regulatory decision making; Gene flow; EFSA guidance; Environmental Risk Assessment
资金
- Lorentz Center of Leiden University
- Netherlands Organization for Scientific Research (NWO) through the ERGO program
Research into introgression, the permanent incorporation of alleles of one species into another, is flourishing and gives new insights into evolution and speciation. The possible transfer of transgenes from crop species to wild relatives is of major concern for regulators. Applicants that want to introduce a genetically modified (GM) crop on the European market need to indicate the likelihood of introgression and its anticipated effects in an Environmental Risk Analysis (ERA). The European Food Safety Association (EFSA) and competent authorities of different countries evaluate the ERA. Predicting which crop alleles will or will not be permanently incorporated into wild populations requires, apart from information on seed production of hybrids, information on how these crop alleles are associated with fitness. Advances in genetics open new avenues to address this question in more detail. We argue, however, that, even with the best techniques, predicting introgression from crop to wild species will always have a considerable margin of uncertainty. One must therefore be prudent to demand more detailed research for the ERA, especially since the possible harm of transgenes in natural populations remains so poorly defined by regulators. (C) 2012 Elsevier Ltd. All rights reserved.
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