期刊
ENVIRONMENTAL POLLUTION
卷 243, 期 -, 页码 103-114出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2018.08.063
关键词
Endocrine disrupting compounds; Surface water; Bahe river; Hemiculter leucisculus; Ecological risk; Estrogenic effect
资金
- National Natural Science Foundation of China [31670523]
This study investigated selected steroidal and phenolic endocrine disrupting compounds (EDCs) in the surface water of the Bahe River (China) using gas chromatography mass spectrometry (GC-MS). Their effect on the wild sharpbelly Hemiculter leucisculus was investigated. The concentrations of 4-t-octylphenol, nonylphenol, bisphenol-A, estrone, 17 beta-estradiol, 17 alpha-Ethinylestradiol, and estriol were up to 126.0, 634.8,1573.1, 55.9, 23.9, 31.5, and 5.2 ng Lg(-1) in the surface water, and up to 26.4, 103.5, 146.9, 14.2, 9.3,13.8, and 1.3 ng g(-1) in the fish muscle tissue, respectively. High estrogen equivalent levels and hazard quotients were found in the middle and lower reaches of the river, and the pollution in these regions caused enhanced growth conditions, inhibition of gonad growth, and suppression of spermatogenesis in H. leucisculus. The up-regulation of Vitellogenin mRNA expression in male fish, collected from relatively heavily EDCs contaminated areas, indicates a potential estrogenic effect. The differential expression profiles of genes related to steroidogenesis at all sampling sites suggests that these endpoints may play an important role for the pollution monitoring of estrogenic EDCs in the Bahe River. (C) 2018 Elsevier Ltd. All rights reserved.
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