期刊
ENVIRONMENTAL POLLUTION
卷 184, 期 -, 页码 515-522出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2013.10.005
关键词
Polycyclic aromatic hydrocarbons; Dietary exposure; Urinary excretion; Biomarkers
资金
- National Science Foundation of China [41101490, 41130754, 41001343]
- NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [P42ES016465] Funding Source: NIH RePORTER
Daily dietary and inhalation exposures to 16 parent polycyclic aromatic hydrocarbons (PAHs) and urinary excretion of 13 monohydroxy metabolites (OHPAHs) were monitored for 12 non-smoking university students in Beijing, China, during a controlled feeding experiment. The relationship between the urinary excretion of OHPAHs and the uptake of PAHs was investigated. The results suggest severe exposure of the subjects to PAHs via both dietary and inhalation pathways. Large increase of most urinary OHPAHs occurred after the ingestion of lamb kabob. Higher concentrations of OHPAHs were observed for female subjects, with the intakes of parent PAHs lower than those by males, likely due to the gender differences in metabolism. It appears that besides 1-PYR, metabolites of PHE could also be used as biomarkers to indicate the short-term dietary exposure to PAHs and urinary 3-BaA may serve as the biomarker for inhalation intake of high molecular weight PAHs. (C) 2013 Elsevier Ltd. All rights reserved.
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