期刊
ENVIRONMENTAL POLLUTION
卷 162, 期 -, 页码 91-97出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2011.10.016
关键词
Urban runoff; Galaxolide (HHCB); Heavy metal; Oxidative stress; Biochemical biomarker
资金
- National Natural Science Foundation of China [21037002]
The objective of this study was to assess potential toxic effects of simulated urban runoff on Carassius auratus using oxidative stress biomarkers. The activity of antioxidant enzymes including superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT), and the content of malondialdehyde (MDA) in the liver of C auratus were analyzed after a 7-, 14- and 21-day exposure to simulated urban runoff containing galaxolide (HHCB) and cadmium (Cd). The results showed that the activity of antioxidant enzymes and the content of MDA increased significantly exposed to the simulated urban runoff containing HHCB alone or mixture of HHCB and Cd. The activity of the investigated enzymes and the content of MDA then returned to the blank level over a longer period of exposure. The oxidative stress could be obviously caused in the liver of C. auratus under the experimental conditions. This could provide useful information for toxic risk assessment of urban runoff. (C) 2011 Elsevier Ltd. All rights reserved.
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