期刊
ENVIRONMENTAL POLLUTION
卷 159, 期 7, 页码 1914-1922出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2011.03.030
关键词
Bivalve; Exposure biomarkers; Effect biomarkers; Multivariate analysis; Integrated sediment quality
资金
- Spanish Ministry of Education
- Spanish Ministry of Science and Innovation [CTM2008-06344-C03-02/TECNO, CTM2008-06344-C03-03/TECNO]
- Junta de Andalucia [P08-556 RNM-3924]
Biomarkers comprising activities of biotransformation enzymes (ethoxyresorufin-O-deethylase-EROD-, dibenzylfluorescein dealkylase -DBF-, glutathione S-transferase -GST), antioxidant enzymes (glutathione reductase -GR- and glutathione peroxidase -GPX), lipid peroxidation -LPO- and DNA strand breaks were analyzed in the clam Ruditapes philippinarum caged at Cadiz Bay, Santander Bay and Las Palmas de Gran Canaria (LPGC) Port (Spain). Sediments were characterized. Digestive gland was the most sensitive tissue to sediment contamination. In Cadiz Bay, changes in LPO regarding day 0 were related with metals. In LPGC Port, DBF, EROD, and GST activity responses suggested the presence of undetermined contaminants which might have led to DNA damage. In Santander Bay, PAHs were related with EROD activity, organic and metal contamination was found to be associated with GR and GST activities and DNA damage presented significant (p < 0.05) induction. R. philippinarum was sensitive to sediment contamination at biochemical level. Biomarkers allowed chemical exposure and sediment quality assessment. (C) 2011 Elsevier Ltd. All rights reserved.
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